Abstract:The period from the late Qing Dynasty to the Republic of China was an important turning point in Chinese history, during which the urban planning and construction of Guangzhou jointly promoted its transformation into a modern city. By sorting out the important events and historical documents of Guangzhou's urban planning and construction from 1860 to 1937 (from the Second Opium War to the eve of the Chinese People's War of Resistance Against Japanese Aggression), the evolution process and characteristics of Guangzhou's urban pattern and morphology were discussed, and an in-depth explanation was made from four aspects of urban clusters, road system, central axis, and public green space. Finally, the law of urban morphology development and change in Guangzhou during this period was obtained: on the basis of retaining the original urban core and landscape structure, the city gradually developed towards the east and south after the demolition of ramparts, forming a modern urban spatial pattern with dominance, openness, and efficiency, laying the foundation for the future urban morphology and development pattern.